Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Graphene sheet OEM supplier Vietnam
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Insole ODM factory in Taiwan
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.One-stop OEM/ODM solution provider Vietnam
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.One-stop OEM/ODM solution provider Taiwan
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.High-performance graphene insole OEM factory Taiwan
Hundred-kilobase fragment deletions in microalgae by Cas9 cleavages. This figure was made using BioRender. Credit: LIU Yang Genome-Edited Algae May Power the Future of Sustainable Biofuel A single-celled alga undergoes genome surgery to remove non-essential parts. This can lead to a most efficient cellular factory for producing sustainable biofuels from sunlight and carbon dioxide. Researchers from the Qingdao Institute of BioEnergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have stripped hundred-kilobase genome from a type of oil-producing microalgae, knocking out genes non-essential for it to function. By doing so, they have created a “genome scalpel” that can trim microalgal genomes rapidly and creatively. The ‘minimal genome’ microalgae produced is potentially useful as a model organism for further study of the molecular and biological function of every gene, or as a ‘chassis’ strain for synthetic biologists to augment for customized production of biomolecules such as biofuels or bioplastics. The study was published in The Plant Journal on March 14, 2021. Creation of a ‘minimal genome’ — a genome stripped of all duplicated or apparently non-functional ‘junk genes’ — can be very useful for investigating fundamental questions about genetic function and for designing cell factories that produce valuable compounds. Such minimal genomes have been created for simple organisms, but rarely for eukaryotic organisms, including algae or plants. In higher eukaryotes, “junk” regions can take up to 70 percent of the genome. Deleting what only appears to be “junk genes” in fact can have harmful effects on the organism or even kill it. For the first time, researchers from QIBEBT have produced a genome with targeted deletions, of hundred kilobases in size each, for a type of algae called Nannochloropsis oceanica. Biofuel Potential of Engineered Microalgae N. oceanica are microalgae (single-celled algae) that have tremendous potential for production of biofuels, biomaterials, and other platform chemicals in a renewable and sustainable manner while reducing greenhouse gas emissions. However, realizing the potential of these microalgae requires extensive genetic engineering of the organism to maximize yields and minimize production costs. The QIBEBT team first identified the non-essential chromosomal regions — ones whose genes were rarely expressed, or activated. They identified ten such ‘low-expression regions’, or LERs. They then used CRISPR-Cas9 gene-editing technique to snip out two of the largest LERs — over 200 kilobases in size. “Despite the all snipping, the microalgae still showed essentially normal growth, lipid content, fatty acid saturation levels and photosynthesis,” said study first-author WANG Qintao, of the Single-Cell Center (SCC) in the QIBEBT. “In some cases, there was even a slightly higher growth rate and biomass productivity than the organism in the wild.” “We interestingly found normal telomeres in the telomere-deletion mutants of Chromosome 30,” said the corresponding author XU Jian, of the SCC in QIBEBT. “This phenomenon implies the losing of distal part of chromosome may induce telomere regeneration.” Already, the substantially snipped genome should serve as a closer-to-minimal genome in Nannochloropsis, which can serve as the chassis strain for customized production of biomolecules using further metabolic engineering atop this chassis. Now that they have proven they can strip down the genome of such a complex eukaryote, the researchers now want to see if they can snip out still further LERs and other non-lethal regions, to craft a fully minimal Nannochloropsis that makes biofuels from CO2 with the highest efficiency. Reference: “Genome engineering of Nannochloropsis with hundred‐kilobase fragment deletions by Cas9 cleavages” by Qintao Wang, Yanhai Gong, Yuehui He, Yi Xin, Nana Lv, Xuefeng Du, Yun Li, Byeong‐ryool Jeong and Jian Xu, 14 March 2021, The Plant Journal. DOI: 10.1111/tpj.15227
For the first time, MIT neuroscientists have identified a population of neurons in the human brain that light up when you hear singing, but not other types of music. Credit: iStockphoto, edited by MIT News MIT neuroscientists have identified a population of neurons in the human brain that respond to singing but not other types of music. For the first time, MIT neuroscientists have identified a population of neurons in the human brain that lights up when we hear singing, but not other types of music. These neurons, found in the auditory cortex, appear to respond to the specific combination of voice and music, but not to either regular speech or instrumental music. Exactly what they are doing is unknown and will require more work to uncover, the researchers say. “The work provides evidence for relatively fine-grained segregation of function within the auditory cortex, in a way that aligns with an intuitive distinction within music,” says Sam Norman-Haignere, a former MIT postdoc who is now an assistant professor of neuroscience at the University of Rochester Medical Center. The work builds on a 2015 study in which the same research team used functional magnetic resonance imaging (fMRI) to identify a population of neurons in the brain’s auditory cortex that responds specifically to music. In the new work, the researchers used recordings of electrical activity taken at the surface of the brain, which gave them much more precise information than fMRI. “There’s one population of neurons that responds to singing, and then very nearby is another population of neurons that responds broadly to lots of music. At the scale of fMRI, they’re so close that you can’t disentangle them, but with intracranial recordings, we get additional resolution, and that’s what we believe allowed us to pick them apart,” says Norman-Haignere. Norman-Haignere is the lead author of the study, which was published on February 22, 2022, in the journal Current Biology. Josh McDermott, an associate professor of brain and cognitive sciences, and Nancy Kanwisher, the Walter A. Rosenblith Professor of Cognitive Neuroscience, both members of MIT’s McGovern Institute for Brain Research and Center for Brains, Minds and Machines (CBMM), are the senior authors of the study. Neural Recordings In their 2015 study, the researchers used fMRI to scan the brains of participants as they listened to a collection of 165 sounds, including different types of speech and music, as well as everyday sounds such as finger tapping or a dog barking. For that study, the researchers devised a novel method of analyzing the fMRI data, which allowed them to identify six neural populations with different response patterns, including the music-selective population and another population that responds selectively to speech. In the new study, the researchers hoped to obtain higher-resolution data using a technique known as electrocorticography (ECoG), which allows electrical activity to be recorded by electrodes placed inside the skull. This offers a much more precise picture of electrical activity in the brain compared to fMRI, which measures blood flow in the brain as a proxy of neuron activity. “With most of the methods in human cognitive neuroscience, you can’t see the neural representations,” Kanwisher says. “Most of the kind of data we can collect can tell us that here’s a piece of brain that does something, but that’s pretty limited. We want to know what’s represented in there.” Electrocorticography cannot typically be performed in humans because it is an invasive procedure, but it is often used to monitor patients with epilepsy who are about to undergo surgery to treat their seizures. Patients are monitored over several days so that doctors can determine where their seizures are originating before operating. During that time, if patients agree, they can participate in studies that involve measuring their brain activity while performing certain tasks. For this study, the MIT team was able to gather data from 15 participants over several years. For those participants, the researchers played the same set of 165 sounds that they used in the earlier fMRI study. The location of each patient’s electrodes was determined by their surgeons, so some did not pick up any responses to auditory input, but many did. Using a novel statistical analysis that they developed, the researchers were able to infer the types of neural populations that produced the data that were recorded by each electrode. “When we applied this method to this data set, this neural response pattern popped out that only responded to singing,” Norman-Haignere says. “This was a finding we really didn’t expect, so it very much justifies the whole point of the approach, which is to reveal potentially novel things you might not think to look for.” That song-specific population of neurons had very weak responses to either speech or instrumental music, and therefore is distinct from the music- and speech-selective populations identified in their 2015 study. Music in the Brain In the second part of their study, the researchers devised a mathematical method to combine the data from the intracranial recordings with the fMRI data from their 2015 study. Because fMRI can cover a much larger portion of the brain, this allowed them to determine more precisely the locations of the neural populations that respond to singing. “This way of combining ECoG and fMRI is a significant methodological advance,” McDermott says. “A lot of people have been doing ECoG over the past 10 or 15 years, but it’s always been limited by this issue of the sparsity of the recordings. Sam is really the first person who figured out how to combine the improved resolution of the electrode recordings with fMRI data to get better localization of the overall responses.” The song-specific hotspot that they found is located at the top of the temporal lobe, near regions that are selective for language and music. That location suggests that the song-specific population may be responding to features such as the perceived pitch, or the interaction between words and perceived pitch, before sending information to other parts of the brain for further processing, the researchers say. The researchers now hope to learn more about what aspects of singing drive the responses of these neurons. They are also working with MIT Professor Rebecca Saxe’s lab to study whether infants have music-selective areas, in hopes of learning more about when and how these brain regions develop. Reference: “A neural population selective for song in human auditory cortex” by Sam V. Norman-Haignere, Jenelle Feather, Dana Boebinger, Peter Brunner. Anthony Ritaccio, Josh H. McDermott, Gerwin Schalk and Nancy Kanwisher, 22 February 2022, Current Biology. DOI: 10.1016/j.cub.2022.01.069 The research was funded by the National Institutes of Health, the U.S. Army Research Office, the National Science Foundation, the NSF Science and Technology Center for Brains, Minds, and Machines, the Fondazione Neurone, and the Howard Hughes Medical Institute.
Scientists have developed a method to genetically modify plants to produce human milk oligosaccharides, which could lead to more nutritious and cheaper infant formulas that mimic the benefits of breast milk more closely. Genetically engineered plants could soon produce human milk sugars, making infant formula healthier and more affordable. Approximately 75% of babies drink infant formula during their first six months, either exclusively or as a supplement to breastfeeding. While these formulas provide essential nutrients, they lack the roughly 200 prebiotic sugar molecules found in human breast milk, which are key to preventing diseases and fostering healthy gut bacteria. Since most of these sugars are difficult to synthesize, current formulas fail to replicate breast milk’s complete nutritional profile. Researchers at the University of California, Berkeley and the University of California, Davis have made significant progress in bridging this gap by genetically engineering plants to produce these crucial sugars, known as human milk oligosaccharides (HMOs). Their study, recently published in the journal Nature Food, could help create a healthier, more affordable infant formula. The Science of Engineering Sugar Metabolism in Plants “Plants are these phenomenal organisms that take sunlight and carbon dioxide from our atmosphere and use them to make sugars. And they don’t just make one sugar — they make a whole diversity of simple and complex sugars,” said study senior author Patrick Shih, an assistant professor of plant and microbial biology and an investigator at UC Berkeley’s Innovative Genomics Institute. “We thought, since plants already have this underlying sugar metabolism, why don’t we try rerouting it to make human milk oligosaccharides?” All complex sugars — including human milk oligosaccharides — are made from building blocks of simple sugars, called monosaccharides, which can be linked together to form a vast array of chains and branched chains. What makes human milk oligosaccharides unique are the specific set of linkages, or rules, for connecting simple sugars together that are found in these molecules. In a new study, scientists reprogrammed Nicotiana benthamiana plants to produce a diverse array of beneficial sugars that are found in breast milk, called human milk oligosaccharides. Credit: Collin Barnum Breakthrough in Human Milk Oligosaccharides Production To convince plants to make human milk oligosaccharides, study first author Collin Barnum engineered the genes responsible for the enzymes that make these specific linkages. In collaboration with Daniela Barile, David Mills, and Carlito Lebrilla at UC Davis, he introduced the genes into the Nicotiana benthamiana plant, a close relative of tobacco. The genetically modified plants produced 11 known human milk oligosaccharides, along with a variety of other complex sugars with similar linkage patterns. “We made all three major groups of human milk oligosaccharides,” Shih said. “To my knowledge, no one has ever demonstrated that you could make all three of these groups simultaneously in a single organism.” Barnum then worked to create a stable line of N. benthamiana plants that were optimized to produce a single human milk oligosaccharide called LNFP1. “LNFP1 is a five-monosaccharide-long human milk oligosaccharide that is supposed to be really beneficial, but so far cannot be made at scale using traditional methods of microbial fermentation,” said Barnum, who completed the work as a graduate student at UC Davis. “We thought that if we could start making these larger, more complex human milk oligosaccharides, we could solve a problem that that industry currently can’t solve.” Towards Commercializing Plant-based Human Milk Oligosaccharides Currently, a small handful of human milk oligosaccharides can be manufactured using engineered E. coli bacteria. However, isolating the beneficial molecules from other toxic byproducts is a costly process, and only a limited number of baby formulas include these sugars in their mixtures. As part of the study, Shih and Barnum worked with collaborator Minliang Yang at North Carolina State University to estimate the cost of producing human milk oligosaccharides from plants at an industrial scale and found that it would likely be cheaper than using microbial platforms. “Imagine being able to make all the human milk oligosaccharides in a single plant. Then you could just grind up that plant, extract all the oligosaccharides simultaneously and add that directly into infant formula,” Shih said. “There would be a lot of challenges in implementation and commercialization, but this is the big goal that we’re trying to move toward.” Reference: “Engineered plants provide a photosynthetic platform for the production of diverse human milk oligosaccharides” by Collin R. Barnum, Bruna Paviani, Garret Couture, Chad Masarweh, Ye Chen, Yu-Ping Huang, Kasey Markel, David A. Mills, Carlito B. Lebrilla, Daniela Barile, Minliang Yang and Patrick M. Shih, 13 June 2024, Nature Food. DOI: 10.1038/s43016-024-00996-x Funding: This work was supported in part by the National Institutes of Health, the U.S. Department of Energy, and the National Center for Complementary and Integrative Health.
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